Prognosis of atrial fibrillation radiofrequency ablation: Iodine-123-MIBG cardiac innervation imaging
نویسندگان
چکیده
Abstract Funding Acknowledgements Type of funding sources: Foundation. Main source(s): Russian Science Foundation BACKGROUND To date, radiofrequency catheter ablation (RFCA) atrial fibrillation (AF) is a valuable treatment option. So far there are no clear predictors the effectiveness AF ablation. Nowadays, association cardiac sympathetic nervous system and development maintenance has been showed. The between сardiac impairment, assessed by 123I-MIBG scintigraphy RFCA was shown previously. However, lack data concerning to prognostic value MIBG in patients with different forms – persistent (PAF) long-standing (LSPAF). PURPOSE study significance efficacy AF. METHODS enrolled 36 drug-resistant (both (n = 20) 16) forms). All had comorbidity as chronic coronary syndrome hypertension. A comparison group 10) also study. It includes arterial hypertension (without arrhythmia). underwent 99mTc-MIBI evaluate activity myocardial perfusion, respectively. Patients performed RFCA. After 1 year follow-up were examined for recurrence. recurrence considered be an at least 30 sec duration on 12-lead ECG or Holter monitoring. RESULTS During period, recurrences reported 7 (35%) PAF 8 (50%) LSPAF patients. According multivariate analysis only high pre-ablation washout rate (WR) (OR: 1.668; 95% CI: 1.093–2.548) large 123I-MIBG/99mTc-MIBI mismatch score 2.155; 1.192–3.897) independent after ROC indicated that higher WR ≥ 20.8% (AUC: 0.968; Sensitivity: 100 %; Specificity: 45%; p < 0.05) larger 12.5 % 0.942; 81 28 risk CONCLUSION In incidence arrhythmia associated impaired activity. values can predict innervation/perfusion terms
منابع مشابه
Iodine-123 mIBG Imaging for Predicting the Development of Atrial Fibrillation.
OBJECTIVES we investigated whether cardiac sympathetic nervous system (SNS) activity measured by iodine-123 meta-iodobenzylguanidine ((123)I-mIBG) imaging would be associated with both the occurrence of heart failure (HF) and the transit to permanent atrial fibrillation (AF) in patients with paroxysmal AF. BACKGROUND atrial fibrillation occurs suddenly and transiently and can persist, and res...
متن کاملMyocardial Iodine-123-Metaiodobenzylguanidine (I-MIBG) Imaging in Brugada Syndrome
(I-MIBG) Imaging in Brugada Syndrome To the Editor: We read with interest a recent article in Circulation by Wichter et al1 on cardiac autonomic dysfunction in Brugada syndrome. The authors demonstrated that regionally reduced iodine-123-metaiodobenzylguanidine (I-MIBG) uptake in the inferior and septal left ventricular wall was present in 8 (47%) of 17 patients with Brugada syndrome but in non...
متن کاملMyocardial Iodine-123-Metaiodobenzylguanidine (I-MIBG) Imaging in Brugada Syndrome
(I-MIBG) Imaging in Brugada Syndrome To the Editor: We read with interest a recent article in Circulation by Wichter et al1 on cardiac autonomic dysfunction in Brugada syndrome. The authors demonstrated that regionally reduced iodine-123-metaiodobenzylguanidine (I-MIBG) uptake in the inferior and septal left ventricular wall was present in 8 (47%) of 17 patients with Brugada syndrome but in non...
متن کاملMyocardial iodine-123-metaiodobenzylguanidine (123I-MIBG) imaging in Brugada syndrome.
(I-MIBG) Imaging in Brugada Syndrome To the Editor: We read with interest a recent article in Circulation by Wichter et al1 on cardiac autonomic dysfunction in Brugada syndrome. The authors demonstrated that regionally reduced iodine-123-metaiodobenzylguanidine (I-MIBG) uptake in the inferior and septal left ventricular wall was present in 8 (47%) of 17 patients with Brugada syndrome but in non...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Echocardiography
سال: 2021
ISSN: ['2047-2412', '2047-2404']
DOI: https://doi.org/10.1093/ehjci/jeaa356.371